Article

SMARCD1 is a “Goldilocks” metastasis modifier

2024-01-29

Abstract excerpt

<h4> Abstract </h4> Breast cancer is the most frequently diagnosed cancer worldwide, constituting around 15% of all diagnosed cancers in 2023. The predominant cause of breast cancer-related mortality is metastasis to distant essential organs, and a lack of metastasis-targeted therapies perpetuates dismal outcomes for late-stage patients. However, through our use of meiotic genetics to study inherited transcripti...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a29a6fa2-a6fb-5f3b-ab5c-00d0abb6a94a
DOI: 10.1101/2024.01.24.577061

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SMARCD1 is a “Goldilocks” metastasis modifierDOI 10.1101/2024.01.24.577061Read

Identification of metastasis driver genes by massive parallel sequencing of successive steps of breast cancer progressionSemantic proximity Read

Metastasis suppressors in breast cancers: mechanistic insights and clinical potentialSemantic proximity Read

Prediction of Molecular Mechanisms of Breast Cancer MetastasisSemantic proximity Read

Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancerSemantic proximity Read

MACC1—the first decade of a key metastasis molecule from gene discovery to clinical translationSemantic proximity Read

<i>WDR88</i> , <i>CCDC11</i> , and <i>ARPP21</i> genes indulge profoundly in the desmoplastic retort to prostate and breast cancer metastasisSemantic proximity Read

LSM4 drives the progression of triple-negative breast cancer through alternative splicingSemantic proximity Read

Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor.Semantic proximity Read

A Rare Subset of Primary Tumor Cells with Concomitant Hyperactivation of Extracellular Matrix Remodeling and dsRNA-IFN1 Signaling Metastasizes in Breast CancerSemantic proximity Read

Pan-cancer drivers of metastasisSemantic proximity Read

The gene desert mammary carcinoma susceptibility locus Mcs1a regulates Nr2f1 modifying mammary epithelial cell differentiation and proliferation.Semantic proximity Read

Expanded detection and impact of <i>BAP1</i> alterations in cancerSemantic proximity Read