Article

Tumour mutations in long noncoding RNAs enhance cell fitness

2022-05-11

Abstract excerpt

<title>Abstract</title> <p>Long noncoding RNAs (lncRNAs) can act as tumour suppressor or oncogenes to contrast/promote tumour cell proliferation via RNA-dependent mechanisms. Recently, genome sequencing has identified elevated densities of tumour somatic single nucleotide variants (SNVs) in lncRNA genes. However, this has been attributed to phenotypically-neutral “passenger” processes, and the existence of positi...

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Literature Corpus work: 829d2f0a-01f7-5a5c-845a-2ca510e0b6f9
DOI: 10.21203/rs.3.rs-1481666/v1

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