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Article

The pan-cancer lncRNA PLANE regulates an alternative splicing program to promote cancer pathogenesis

2020-12-11

Abstract excerpt

<title>Abstract</title> <p>Genomic amplification of the distal portion of chromosome 3q, which encodes a number of oncogenic proteins, is one of the most frequent chromosomal abnormalities in malignancy. Here we functionally characterise a non-protein product of the 3q region, the long noncoding RNA (lncRNA) PLANE, which is upregulated in diverse cancer types through copy number gain as well as E2F1-mediated tran...

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Identifiers and source

Literature Corpus work
11548ea4-f33e-5134-92d4-88745a1038da
DOI
10.21203/rs.3.rs-122179/v1
Open publication

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The pan-cancer lncRNA PLANE regulates an alternative splicing program to promote cancer pathogenesisDOI 10.21203/rs.3.rs-122179/v1
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