Article

Targeted and untargeted proteomics-based comparison of adenoviral infected hCMEC/D3 and hBMEC as a human blood-brain barrier model to study the OATP2B1 transporter

2024-12-05

Abstract excerpt

<title>Abstract</title> <p>The blood-brain barrier (BBB) is essential for central nervous system (CNS) homeostasis by regulating permeability between the bloodstream and brain. This study evaluates the immortalized human brain capillary endothelial cell lines hCMEC/D3 and hBMEC for their use as an <italic>in vitro</italic> BBB model to investigate the OATP2B1 transporter following adenoviral infection. We assesse...

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Literature Corpus work: 3664f8d4-ba37-5f56-9538-582b583de19c
DOI: 10.21203/rs.3.rs-5388233/v1

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