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Efflux proteins at the blood–brain barrier: review and bioinformatics analysis

8 May 2017

Abstract excerpt

1. Efflux proteins at the blood-brain barrier provide a mechanism for export of waste products of normal metabolism from the brain and help to maintain brain homeostasis. They also prevent entry into the brain of a wide range of potentially harmful compounds such as drugs and xenobiotics. 2. Conversely, efflux proteins also hinder delivery of therapeutic drugs to the brain and central nervous system used to treat...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28481715
DOI: 10.1080/00498254.2017.1328148

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