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Exploring ITM2A as a new potential target for brain delivery

21 Mar 2022

Abstract excerpt

BACKGROUND: Integral membrane protein 2A (ITM2A) is a transmembrane protein expressed in a variety of tissues; little is known about its function, particularly in the brain. ITM2A was found to be highly enriched in human brain versus peripheral endothelial cells by transcriptomic and proteomic studies conducted within the European Collaboration on the Optimization of Macromolecular Pharmaceutical (COMPACT)...

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PMID: 35313913
DOI: 10.1186/s12987-022-00321-3

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