Article

Effect of riboflavin supplementation on blood pressure and possible effect modification by the MTHFR C677T polymorphism: a randomised trial in rural Gambia

2020-08-24

Abstract excerpt

<h4>Introduction: </h4> Emerging evidence links a functional polymorphism in the methylenetetrahydrofolate reductase ( MTHFR ) gene (rs1801133) with hypertension in adults. This variant reduces the affinity of MTHFR for its cofactor flavin-adenine dinucleotide (FAD) which is derived from riboflavin. Previous work has demonstrated a blood pressure (BP)-lowering effect of riboflavin in Irish adults with the MTHFR...

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Literature Corpus work: 3647087b-9ddc-5ace-a1c0-0edbca332a5a
DOI: 10.12688/f1000research.25113.1

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