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Riboflavin lowers blood pressure in cardiovascular disease patients homozygous for the 677C→T polymorphism in MTHFR

13 Feb 2010

Abstract excerpt

OBJECTIVE: The purpose was to examine the effect of intervention with riboflavin (a cofactor for MTHFR) on blood pressure in patients homozygous (TT genotype) for the common 677C-->T polymorphism in MTHFR. METHODS: We investigated 197 premature cardiovascular disease patients, prescreened for the MTHFR 677C-->T polymorphism, from an original cohort of 404 to select those with the TT genotype (n = 60) and a...

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PMID: 19952781
DOI: 10.1097/hjh.0b013e328334c126

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