Article

Simultaneous profiling of native-state proteomes and transcriptomes of neural cell types using proximity labeling

2025-02-01

Abstract excerpt

Deep molecular phenotyping of cells at transcriptomic and proteomic levels is an essential first step to understanding cellular contributions to development, aging, injury, and disease. Since proteome and transcriptome level abundances only modestly correlate with each other, complementary profiling of both is needed. We report a novel method called simultaneous protein and RNA –omics (SPARO) to capture the cell t...

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Literature Corpus work: 36430a82-9f86-5d68-939b-75eabdf88375
DOI: 10.1101/2025.01.29.635500

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