Article

Mapping Human Tissues with Highly Multiplexed RNA in situ Hybridization

2023-08-18

Abstract excerpt

In situ transcriptomic techniques promise a holistic view of tissue organization and cell-cell interactions. Recently there has been a surge of multiplexed RNA in situ techniques but their application to human tissues and clinical biopsies has been limited due to their large size, general lower tissue quality and high background autofluorescence. Here we report DART-FISH, a versatile padlock probe-based technology...

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Literature Corpus work: f1df0499-f5be-5c08-9929-e4b3757ce6ed
DOI: 10.1101/2023.08.16.553610

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