Article

Neuroinflammatory Stress Preferentially Impacts Synaptic MAPK Signaling and Mitochondria in Excitatory Neurons

2025-10-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Understanding synapse-specific effects of neuroinflammation can provide mechanistic and therapeutically relevant insights across the spectrum of neurological diseases. <h4>Methods</h4> We applied neuron-specific proteomic biotinylation in vivo , differential centrifugation of brain for crude synaptosome enrichment (P2 fraction) and mass spectrometry (MS) analysis of biotin...

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Literature Corpus work: dbfca1dd-dfc6-5b5f-9b67-477b7e550d01
DOI: 10.1101/2025.10.03.680087

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