Article

Prostaglandin E2 Enhances Aged Hematopoietic Stem Cell Function

2021-02-11

Abstract excerpt

<title>Abstract</title> <p>Aging of hematopoiesis is associated with increased frequency and clonality of hematopoietic stem cells (HSCs), along with functional compromise and myeloid bias, with donor age being a significant variable in survival after HSC transplantation. No clinical methods currently exist to enhance aged HSC function, and little is known regarding how aging affects molecular responses of HSCs t...

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Literature Corpus work: 363ded8c-5cdb-5305-8a8e-bd4644d03350
DOI: 10.21203/rs.3.rs-224253/v1

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