Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prostaglandin E2: Making More of Your Marrow

15 Dec 2007

Abstract excerpt

We have recently demonstrated through a chemical screen in the zebrafish embryo that prostaglandin E2 (PGE2) is an evolutionarily conserved regulator of hematopoietic stem cell (HSC) number. These results have further been confirmed by in vitro and in vivo studies in the murine model. Bioactive PGE2 derivatives have potential clinical application to accelerate recovery of the hematopoietic system following...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenesis and VEGF in Cancer
Share to Hematopoietic Stem Cell Transplantation
Share to Zebrafish Biomedical Research Applications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18075310
DOI: 10.4161/cc.6.24.5129

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prostaglandin E2: Making More of Your MarrowPMID 18075310Read ↗

Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasisSemantic proximity Read ↗

Prostaglandin E2 Enhances Aged Hematopoietic Stem Cell FunctionSemantic proximity Read ↗

Lineage-Specific Hematopoietic Growth FactorsSemantic proximity Read ↗

Ex vivo expansion and functional activity preservation of adult hematopoietic stem cells by a diarylheptanoid from Curcuma comosa.Semantic proximity Read ↗

Assaying hematopoiesis using zebrafish.Semantic proximity Read ↗

BMP4: Its Role in Development of the Hematopoietic System and Potential as a Hematopoietic Growth FactorSemantic proximity Read ↗

Hematopoietic stem cell division is governed by distinct RUNX1 binding partnersSemantic proximity Read ↗

Dissection of vertebrate hematopoiesis using zebrafish thrombopoietinSemantic proximity Read ↗

Prostaglandin E1 and Its Analog Misoprostol Inhibit Human CML Stem Cell Self-Renewal via EP4 Receptor Activation and Repression of AP-1Semantic proximity Read ↗

HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cellsSemantic proximity Read ↗

Prostaglandin E2 regulates B cell proliferation through a candidate tumor suppressor, Ptger4Semantic proximity Read ↗

Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/SCID transplantationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.