Article

Development of a Novel Anti-CD44 Variant 8 Monoclonal Antibody C<sub>44</sub>Mab-94 against Gastric Carcinomas

2023-05-15

Abstract excerpt

Gastric cancer (GC) is the third leading cause of cancer-related deaths worldwide. GC with peritoneal metastasis exhibits a poor prognosis due to the lack of diagnostic biomarkers and effective therapy. A comprehensive analysis of malignant ascites identified the genomic alterations and significant amplifications of cancer driver genes, including CD44. CD44 and its splicing variants are overexpressed in tumors, an...

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Literature Corpus work: 362acf60-827b-582c-9f2e-b01f40511899
DOI: 10.20944/preprints202305.0995.v1

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