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CD44 and its implication in neoplastic diseases

23 May 2024

Abstract excerpt

Abstract CD44, a nonkinase single span transmembrane glycoprotein, is a major cell surface receptor for many other extracellular matrix components as well as classic markers of cancer stem cells and immune cells. Through alternative splicing of CD44 gene, CD44 is divided into two isoforms, the standard isoform of CD44 (CD44s) and the variant isoform of CD44 (CD44v). Different isoforms of CD44 participate in...

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PMID: 38783892
DOI: 10.1002/mco2.554

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