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G<sub>4</sub>Mab-9: An Anti-Glypican-4 Monoclonal Antibody for Multiple Applications

2026-06-22

Abstract excerpt

Glypican-4 (GPC4) is a member of the heparan sulfate proteoglycan family and regulates a wide range of growth factor signaling through interactions with heparan sulfate-binding ligands. Pathogenic variants of GPC4 have been identified in human congenital disorders, and dysregula-tion of GPC4 has been reported in human cancer. Therefore, specific anti-GPC4 monoclonal anti-bodies (mAbs) are needed for both basic res...

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Literature Corpus work
acc606bd-4d25-5e5b-9886-b47d9cfac882
DOI
10.20944/preprints202606.1558.v1
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