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Epitope Mapping of an Anti-CD44v4 Monoclonal Antibody (C<sub>44</sub>Mab-108) using Enzyme-Linked Immunosorbent Assay

2023-11-03

Abstract excerpt

CD44 is a type I transmembrane glycoprotein, and possesses various isoforms which are largely classified into CD44 standard and CD44 variant (CD44v) isoforms. Some variant-encoded regions play critical roles in tumor progression. However, the function of CD44 variant 4 (CD44v4)-encoded region has not been fully understood. Using peptide immunization, we developed an anti-CD44v4 mAb, C44Mab-108, which is useful for...

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Literature Corpus work: 118c6acd-9311-598e-9640-7b381a5136b1
DOI: 10.20944/preprints202311.0216.v1

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