Article

Selection of Synthetic Proteins to Modulate the Human Frataxin Function

2022-02-12

Abstract excerpt

<h4>ABSTRACT</h4> Frataxin is a kinetic activator of the mitochondrial supercomplex for iron–sulfur cluster assembly. Low frataxin expression or a decrease in its functionality results in Friedreich’s Ataxia (FRDA). With the aim of creating new molecular tools to study this metabolic pathway, and ultimately, to explore new therapeutic strategies, we have investigated the possibility of obtaining small proteins ex...

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Literature Corpus work: 3629389c-d020-5d35-a961-973b2581e942
DOI: 10.1101/2022.02.11.480108

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