Article

Generalizability of Tau and Amyloid Plasma Biomarkers in Alzheimer’s Disease Cohorts of Diverse Genetic Ancestries

2024-04-12

Abstract excerpt

<h4>Introduction</h4> Plasma phosphorylated threonine-181 of Tau and amyloid beta are biomarkers for differential diagnosis and preclinical detection of Alzheimer disease (AD). Given differences in AD risk across diverse populations, generalizability of existing biomarker data is not assured. <h4>Methods</h4> In 2,086 individuals of diverse genetic ancestries (African American, Caribbean Hispanic, and Peruvians) w...

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Literature Corpus work: 361f045a-e9e1-5591-ab1c-debd2e4ccce8
DOI: 10.1101/2024.04.10.24305617

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