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Article

Plasma phospho-tau217 as a predictive biomarker for Alzheimer’s disease in a large south American cohort

2 Jan 2025

Abstract excerpt

BACKGROUND: Blood-based Alzheimer's disease (AD) biomarkers have been increasingly employed for diagnostic, prognostic, and therapeutic monitoring purposes, due to accuracy in distinguishing AD pathophysiologic process. Compared to other p-tau isoforms, plasma p-tau217 exhibits stronger associations with AD hallmarks in CSF and brain. However, most studies have been conducted in non-Hispanic Whites, limiting our...

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PMID: 39743558
DOI: 10.1186/s13195-024-01655-w

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