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Anti-Tumor Effects of Cecropin A and Drosocin Incorporated into Macrophage-Like Cells Against Hematopoietic Tumors in <i>Drosophila mxc</i> Mutants

2025-01-31

Abstract excerpt

Five major antimicrobial peptides (AMPs) in &lt;i&gt;Drosophila&lt;/i&gt; are induced in &lt;i&gt;multiple sex combs&lt;/i&gt; (&lt;i&gt;mxc&lt;/i&gt;) mutant larvae harboring lymph gland (LG) tumors and exhibit anti-tumor effects. The effects of the other well-known AMPs, Cecropin A and Drosocin, remain unelucidated. We investigated the tumor-elimination mechanism of these AMPs. A half-dose reduction of either &l...

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Literature Corpus work
be48e5b8-2398-5f15-9f2f-67db3ebf3a57
DOI
10.20944/preprints202501.2343.v1
Open publication

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Anti-Tumor Effects of Cecropin A and Drosocin Incorporated into Macrophage-Like Cells Against Hematopoietic Tumors in <i>Drosophila mxc</i> MutantsDOI 10.20944/preprints202501.2343.v1
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