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<i>Drosophila</i> larval models of invasive tumourigenesis for in vivo studies on tumour/peripheral host tissue interactions during cancer cachexia

2021-07-01

Abstract excerpt

Cancer cachexia is a common deleterious paraneoplastic syndrome that represents an area of unmet clinical need, partly due to its poorly understood aetiology and complex multifactorial nature. We have interrogated multiple genetically defined larval Drosophila models of tumourigenesis against key features of human cancer cachexia. Our results indicate that cachectic tissue wasting is dependent on the genetic char...

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Identifiers and source

Literature Corpus work
7575f1e3-196f-5019-851a-69d2127e7a80
DOI
10.1101/2021.07.01.450696
Open publication

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<i>Drosophila</i> larval models of invasive tumourigenesis for in vivo studies on tumour/peripheral host tissue interactions during cancer cachexiaDOI 10.1101/2021.07.01.450696
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