Article

<i>Drosophila</i> Toll links systemic immunity to long-term intestinal function

2018-01-15

Abstract excerpt

The intestine is an organ where immune and metabolic functions are co-ordinated with tissue renewal via progenitor somatic stem cells (PSSCs). How this is achieved is still unclear. We report that in Drosophila , a generalised infection increased PSSC numbers. This was mimicked by expressing a constitutive form of the immune receptor Toll in PSSCs and blocked when Toll was silenced via RNAi. Without infection, ab...

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Literature Corpus work: 1b94e49a-b884-5407-bcb6-11780c10c3a2
DOI: 10.1101/248138

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