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Mouse Models of Cancer

24 Jan 2011

Abstract excerpt

Genetically engineered mouse models have significantly contributed to our understanding of cancer biology. They have proven to be useful in validating gene functions, identifying novel cancer genes and tumor biomarkers, gaining insight into the molecular and cellular mechanisms underlying tumor initiation and multistage processes of tumorigenesis, and providing better clinical models in which to test novel...

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PMID: 20936938
DOI: 10.1146/annurev.pathol.3.121806.154244

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