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Article

The Mouse Models of Human Cancer database (MMHCdb).

Disease models & mechanisms - 1 Apr 2023

Begley Dale A, Krupke Debra M, Sundberg John P, Jocoy Emily L, Richardson Joel E, Neuhauser Steven B, Bult Carol J

Abstract excerpt

The laboratory mouse has served for decades as an informative animal model system for investigating the genetic and genomic basis of cancer in humans. Although thousands of mouse models have been generated, compiling and aggregating relevant data and knowledge about these models is hampered by a general lack of compliance, in the published literature, with nomenclature and annotation standards for genes, alleles,...

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PMID: 36967676
DOI: 10.1242/dmm.050001
PMCID: PMC10120068

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