Article

Retained introns in long RNA-seq reads are not reliably detected in sample-matched short reads

2022-03-12

Abstract excerpt

There is growing interest in retained introns in a variety of disease contexts including cancer and aging. Many software tools have been developed to detect retained introns from short RNA-seq reads, but reliable detection is complicated by overlapping genes and transcripts as well as the presence of unprocessed or partially processed RNAs. We compared introns detected by 5 tools using short RNA-seq reads with int...

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Literature Corpus work: 358b18a7-34ca-5565-b2fb-d9220e623cdc
DOI: 10.1101/2022.03.11.484016

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