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Article

Computational analysis of splicing errors and mutations in human transcripts.

BMC genomics - 14 Jan 2008

Kurmangaliyev Yerbol Z, Gelfand Mikhail S

Abstract excerpt

BACKGROUND: Most retained introns found in human cDNAs generated by high-throughput sequencing projects seem to result from underspliced transcripts, and thus they capture intermediate steps of pre-mRNA splicing. On the other hand, mutations in splice sites cause exon skipping of the respective exon or activation of pre-existing cryptic sites. Both types of events reflect properties of the splicing mechanism....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18194514
DOI: 10.1186/1471-2164-9-13
PMCID: PMC2234086

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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