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A Common Class of Transcripts with 5′-Intron Depletion, Distinct Early Coding Sequence Features, and N <sup>1</sup> -Methyladenosine Modification

2016-06-07

Abstract excerpt

Introns are found in 5’ untranslated regions (5’UTRs) for 35% of all human transcripts. These 5’UTR introns are not randomly distributed: genes that encode secreted, membrane-bound and mitochondrial proteins are less likely to have them. Curiously, transcripts lacking 5’UTR introns tend to harbor specific RNA sequence elements in their early coding regions. To model and understand the connection between coding-reg...

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Literature Corpus work
b7c86cc2-16a0-52b3-9e99-cd9e71731b1a
DOI
10.1101/057455
Open publication

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A Common Class of Transcripts with 5′-Intron Depletion, Distinct Early Coding Sequence Features, and N <sup>1</sup> -Methyladenosine ModificationDOI 10.1101/057455
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