Article

Dermis resident macrophages orchestrate localized ILC2-eosinophil circuitries to maintain their M2-like properties and promote non-healing cutaneous leishmaniasis

2023-04-05

Abstract excerpt

<title>Abstract</title> Tissue-resident macrophages (TRMs) are critical for tissue homeostasis/repair. We previously showed that dermal TRMs produce CCL24 (eotaxin2) which mediates their interaction with IL-4 producing eosinophils, required to maintain their number and M2-like properties in the TH1 environment of the <italic>Leishmania major </italic>infected skin. Here, we unveil another layer of T...

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Literature Corpus work: 3518ab9c-169d-5515-a3c6-b01a7e86fd91
DOI: 10.21203/rs.3.rs-2644705/v1

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Dermis resident macrophages orchestrate localized ILC2-eosinophil circuitries to maintain their M2-like properties and promote non-healing cutaneous leishmaniasisDOI 10.21203/rs.3.rs-2644705/v1Read

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