Article

The metabolic program of inflammatory eosinophils accounts for chronic parasite-induced skin disease

2025-03-01

Abstract excerpt

<h4>ABSTRACT</h4> Eosinophils exert antimicrobial, cytotoxic and immunoregulatory effects, but their function in cutaneous tissue still remains poorly understood. Here, we used a mouse model of chronic cutaneous leishmaniasis caused by the protozoan parasite Leishmania (L.) mexicana to investigate the function and transcriptomic signature of eosinophils in the skin. In C57BL/6 wild-type mice, L. mexicana infect...

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Literature Corpus work: aab61188-5dbb-5237-a81e-4b319f8ac498
DOI: 10.1101/2025.02.28.640104

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