Article

Type 2 innate immunity regulates hair follicle homeostasis to control <i>Demodex</i> pathosymbionts

2021-03-30

Abstract excerpt

Allergic skin diseases are common, but basal roles for type 2 immunity in cutaneous homeostasis are incompletely understood. Here, we show that skin group 2 innate lymphoid cells (ILC2s) are the predominant resident cells that secretes IL-13, which attenuates epithelial cell proliferation during anagen throughout the hair follicle (HF), including in HF stem cells. Although HF are normal in the absence of type 2 im...

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Literature Corpus work: efd680d0-61e1-5fb9-aa19-66a1db9c6892
DOI: 10.1101/2021.03.29.437438

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