Article

Genetics and Environment Distinctively Shape the Human Immune Cell Epigenome

2023-06-30

Abstract excerpt

The epigenomic landscape of human immune cells is dynamically shaped by both genetic factors and environmental exposures. However, the relative contributions of these elements are still not fully understood. In this study, we employed single-nucleus methylation sequencing and ATAC-seq to systematically explore how pathogen and chemical exposures, along with genetic variation, influence the immune cell epigenome. W...

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Literature Corpus work: 3502029f-958a-5bf4-a103-7734dc595160
DOI: 10.1101/2023.06.29.546792

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