Article

Chemotherapy activates inflammasomes to cause inflammation-associated bone loss

2023-10-09

Abstract excerpt

Chemotherapy is a widely used treatment for a variety of solid and hematological malignancies. Despite its success in improving the survival rate of cancer patients, chemotherapy causes significant toxicity to multiple organs, including the skeleton, but the underlying mechanisms have yet to be elucidated. Using tumor-free mouse models, which are commonly used to assess direct off-target effects of anti-neoplastic...

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Literature Corpus work: 34edbab2-d0d0-50de-b1b1-bdb0b5c7acee
DOI: 10.1101/2023.10.06.561196

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