Article

Volumetric Compression Shifts Rho GTPase Balance and Induces Mechanobiological Cell State Transition

2023-10-10

Abstract excerpt

During development and disease progression, cells are subject to osmotic and mechanical stresses that modulate cell volume, which fundamentally influences cell homeostasis and has been linked to a variety of cellular functions. It is not well understood how the mechanobiological state of cells is programmed by the interplay of intracellular organization and complex extracellular mechanics when stimulated by cell v...

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Literature Corpus work: 348424e2-1595-54ca-96a7-a3acdde5f40f
DOI: 10.1101/2023.10.08.561452

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