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InterDILI: interpretable prediction of drug-induced liver injury through permutation feature importance and attention mechanism

2023-08-25

Abstract excerpt

Safety is one of the important factors constraining the distribution of clinical drugs on the market. Drug-induced liver injury (DILI) is the leading cause of safety problems produced by drug side effects. Therefore, the DILI risk of approved drugs and potential drug candidates should be assessed. Currently, in vivo and in vitro methods are used to test DILI risk, but both methods are labor-intensive, time-consumi...

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Literature Corpus work
3476e8f7-f84a-5e4d-a395-2e49940414ba
DOI
10.21203/rs.3.rs-3274827/v1
Open publication

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InterDILI: interpretable prediction of drug-induced liver injury through permutation feature importance and attention mechanismDOI 10.21203/rs.3.rs-3274827/v1
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