Article

Integration of human cell lines gene expression and chemical properties of drugs for Drug Induced Liver Injury prediction

2020-04-01

Abstract excerpt

<title>Abstract</title> <p>Motivation: Drug-induced liver injury (DILI) is one of the primary problems in drug development. Early prediction of DILI can bring a significant reduction in the cost of clinical trials. In this work we examined whether occurrence of DILI can be predicted using gene expression profile in cancer cell lines and chemical properties of drugs. <h4>Methods:</h4> We used gene expression profi...

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Literature Corpus work: 8610b542-362c-505c-9273-4513661e23b5
DOI: 10.21203/rs.3.rs-19658/v1

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