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Article

SARS-CoV-2 infection of olfactory epithelial cells and neurons drives acute lung injury and lethal COVID-19 in mice

2021-12-07

Abstract excerpt

Lethal COVID-19 is associated with respiratory failure that is thought to be caused by acute respiratory distress syndrome (ARDS) secondary to pulmonary infection. To date, the cellular pathogenesis has been inferred from studies describing the expression of ACE2, a transmembrane protein required for SARS-CoV-2 infection, and detection of viral RNA or protein in infected humans, model animals, and cultured cells....

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Literature Corpus work
33e78d6e-ea69-505d-a249-0a55e102c29f
DOI
10.1101/2021.12.04.471245
Open publication

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SARS-CoV-2 infection of olfactory epithelial cells and neurons drives acute lung injury and lethal COVID-19 in miceDOI 10.1101/2021.12.04.471245
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