Article
SARS-CoV-2 infection of olfactory epithelial cells and neurons drives acute lung injury and lethal COVID-19 in mice
2021-12-07
Abstract excerpt
Lethal COVID-19 is associated with respiratory failure that is thought to be caused by acute respiratory distress syndrome (ARDS) secondary to pulmonary infection. To date, the cellular pathogenesis has been inferred from studies describing the expression of ACE2, a transmembrane protein required for SARS-CoV-2 infection, and detection of viral RNA or protein in infected humans, model animals, and cultured cells....
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Identifiers and source
- Literature Corpus work
- 33e78d6e-ea69-505d-a249-0a55e102c29f
- DOI
- 10.1101/2021.12.04.471245
