Article

Preservation of full-length transcripts at ambient temperature using ensilication

2026-04-16

Abstract excerpt

Long-read RNA sequencing can resolve full-length transcript isoforms directly from single molecules, but this capability is contingent on maintaining molecular integrity. Here we show that ensilication, the encapsulation of RNA within a deposited silica matrix, preserves isoform-level fidelity in PacBio Kinnex long-read sequencing after seven days of storage at 40 °C. Pooled human total RNA was profiled across six...

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Literature Corpus work: 33dd21b5-23cd-588f-8931-14fa90db27e7
DOI: 10.64898/2026.04.13.717197

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