Article

Spatially Exploring RNA Biology in Archival Formalin-Fixed Paraffin-Embedded Tissues

2024-02-08

Abstract excerpt

Spatial transcriptomics has emerged as a powerful tool for dissecting spatial cellular heterogeneity but as of today is largely limited to gene expression analysis. Yet, the life of RNA molecules is multifaceted and dynamic, requiring spatial profiling of different RNA species throughout the life cycle to delve into the intricate RNA biology in complex tissues. Human disease-relevant tissues are commonly preserved...

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Literature Corpus work: 19e42bb6-e577-5abf-add6-e5052a286e8d
DOI: 10.1101/2024.02.06.579143

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