Article

Multicellular, IVT-derived, unmodified human transcriptome for nanopore-direct RNA analysis

2023-04-07

Abstract excerpt

<h4>ABSTRACT</h4> Nanopore direct RNA sequencing (DRS) enables measurements of RNA modifications. Modification-free transcripts are a practical and targeted control for DRS, providing a baseline measurement for canonical nucleotides within a matched and biologically derived sequence context. However, these controls can be challenging to generate and carry nanopore-specific nuances that can impact analysis. We pro...

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Literature Corpus work: c7b4400a-1bd3-58e3-8d9f-2d84bcfbc347
DOI: 10.1101/2023.04.06.535889

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