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Epigenetic clocks for mice based on age-associated regions that are conserved between mouse strains and human

2022-03-23

Abstract excerpt

Aging of mice can be tracked by DNA methylation changes at specific sites in the genome. In this study, we used the recently released Infinium Mouse Methylation BeadChip to compare such epigenetic modifications in C57BL/6 (B6) and DBA/2J (DBA) mice. We observed marked differences in age-associated DNA methylation in these commonly used inbred mouse strains, indicating that epigenetic clocks for one strain cannot b...

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Identifiers and source

Literature Corpus work
33d5dd92-3b75-5d33-847a-29f5a371ac28
DOI
10.1101/2022.03.23.485470
Open publication

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Epigenetic clocks for mice based on age-associated regions that are conserved between mouse strains and humanDOI 10.1101/2022.03.23.485470
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