Article

DNA methylation clocks for clawed frogs reveal evolutionary conservation of epigenetic ageing

2022-08-04

Abstract excerpt

<h4>ABSTRACT</h4> DNA methylation-based biomarkers of ageing (epigenetic clocks) have been developed for many mammals, but not yet for amphibian species. We generated DNA methylation data from African clawed frogs ( Xenopus laevis ) and Western clawed frogs ( Xenopus tropicalis ), from adult tissues, whole embryos, and tadpoles. We used an array platform designed for CpGs that are highly conserved in mammals to...

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Literature Corpus work: a27f7597-1607-511a-917e-a6ac852fbfe2
DOI: 10.1101/2022.08.02.502561

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