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The Epigenetic Landscape: From Molecular Mechanisms to Biological Aging

17 Mar 2025

Abstract excerpt

Epigenetics, the study of heritable changes in gene expression that do not involve alterations to the deoxyribonucleic acid (DNA) sequence, plays a pivotal role in cellular function, development, and aging. This review explores key epigenetic mechanisms, including DNA methylation (DNAm), histone modifications, chromatin remodeling, RNA-based regulation, and long-distance chromosomal interactions. These...

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PMID: 40094262
DOI: 10.1089/rej.2024.0102

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