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Germ cell tumors in children

1 Jan 2025

Abstract excerpt

Pediatric germ cell tumors represent a rare but biologically diverse group of neoplasms arising from pluripotent primordial germ cells. The 2022 edition of the WHO Classification of Pediatric Tumors introduced the first organ independent classification of germ cell tumors, reflecting advances in molecular biology, histopathology, and clinical practice. This review highlights the key changes, including the refined...

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PMID: 39779499
DOI: 10.1007/s00428-025-04023-7

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