Article

Glioblastoma embryonic-like stem cells exhibit immune-evasive phenotype

2021-12-09

Abstract excerpt

Glioma stem cells (GSCs) are a subset of cells with self-renewal and tumor-initiating capacities that are thought to participate in drug resistance and immune evasion mechanisms in glioblastoma (GBM). Given GBM heterogeneity, we hypothesized that GSCs might also display cellular hierarchies associated with different degrees of stemness. We evaluated a single-cell RNA-seq glioblastoma dataset ( n = 28) and identif...

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Literature Corpus work: 2f9f9bdc-2bd6-562e-8044-cef7d7c91def
DOI: 10.1101/2021.12.07.471556

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