Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dissecting the molecular pathways of (testicular) germ cell tumour pathogenesis; from initiation to treatment‐resistance

12 May 2011

Abstract excerpt

Human type II germ cell tumours (GCTs) originate from an embryonic germ cell, either as a primordial germ cell or gonocyte. This start determines the biological as well as clinical characteristics of this type of cancer, amongst others their totipotency as well as their overall (exceptional) sensitivity to DNA damaging agents. The histology of the precursor lesion, either carcinoma in situ or gonadoblastoma,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Sexual Differentiation and Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Testicular diseases and treatments

Source

Identifiers

PMID: 21564133
DOI: 10.1111/j.1365-2605.2011.01157.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dissecting the molecular pathways of (testicular) germ cell tumour pathogenesis; from initiation to treatment‐resistancePMID 21564133Read ↗

Human testicular (non)seminomatous germ cell tumours: the clinical implications of recent pathobiological insightsSemantic proximity Read ↗

The biology of germ cell tumors in disorders of sex development.Semantic proximity Read ↗

On the Origin of Testicular Germ Cell Tumors: From Gonocytes to Testicular CancerSemantic proximity Read ↗

Molecular and epigenetic pathogenesis of germ cell tumorsSemantic proximity Read ↗

Pathogenesis and pathobiology of testicular germ cell tumours: a view from a developmental biological perspective with guidelines for pathological diagnosticsSemantic proximity Read ↗

Evolution of Testicular Germ Cell Tumors in the Molecular Era With Histogenetic ImplicationsSemantic proximity Read ↗

Predicting Gonadal Germ Cell Cancer in People with Disorders of Sex Development; Insights from Developmental Biology.Semantic proximity Read ↗

Recent developments in testicular germ cell tumor researchSemantic proximity Read ↗

Development of malignant germ cells - the genvironmental hypothesisSemantic proximity Read ↗

The genomic landscape of testicular germ cell tumours: from susceptibility to treatment.Semantic proximity Read ↗

Developmental model for the pathogenesis of testicular carcinoma <i>in situ</i> : genetic and environmental aspectsSemantic proximity Read ↗

Updating germ cell tumour pathogenesis – the ability of seminomas for FOXA2‐driven extra‐embryonic differentiationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.