Article

Identification of anti-resorptive GPCRs by high-content imaging in human osteoclasts

2024-12-04

Abstract excerpt

Osteoporosis diagnoses are increasing in the ageing population and although several treatments exist, these have several disadvantages, highlighting the need to identify new drug targets. G protein-coupled receptors (GPCRs) are transmembrane proteins whose surface expression and extracellular activation make them desirable drug targets. Our previous studies have identified 144 GPCR genes to be expressed in primary...

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Literature Corpus work: 33b56425-b563-5eb6-89e9-0a6682e936f8
DOI: 10.1101/2024.12.03.626553

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