Article

GPR137B, an orphan G protein-coupled receptor abundantly expressed in osteoclasts, is dispensable for osteoclast differentiation and bone development in mice

2026-06-16

Abstract excerpt

<title>Abstract</title> <p> Osteoclasts are bone-resorbing cells that differentiate from progenitor cells in the bone marrow (BM). In this study, we identified <italic>Gpr137b</italic> , which encodes an orphan G protein-coupled receptor, as a gene whose expression markedly upregulated during mouse and human osteoclast differentiation. Although a previous study reported that <italic>Gpr137b</italic> knockdow...

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Literature Corpus work: ff493733-2228-5e47-88c8-d4a8f8ae53ca
DOI: 10.21203/rs.3.rs-9980622/v1

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