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Article

The endovanilloid/endocannabinoid system: a new potential target for osteoporosis therapy.

Bone - 1 May 2011

Rossi Francesca, Bellini Giulia, Luongo Livio, Torella Marco, Mancusi Silvia, De Petrocellis Luciano, Petrosino Stefania, Siniscalco Dario, Orlando Pierangelo, Scafuro Mariantonietta, Colacurci Nicola, Perrotta Silverio, Nobili Bruno, Di Marzo Vincenzo, Maione Sabatino

Abstract excerpt

Human osteoclasts express functional TRPV1 channels, CB1/CB2 cannabinoid receptors and endocannabinoid/endovanilloid synthetic/catabolic enzymes. Pharmacologic manipulation of this system can modulate osteoclast activity. Here, through multidisciplinary approaches, we demonstrate that enzymes and receptors of the endocannabinoid/endovanilloid system are differently expressed in osteoclasts from menopausal women...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Phospholipase D

Share to Receptor, Cannabinoid, CB1

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Source

Identifiers

PMID: 21237298
DOI: 10.1016/j.bone.2011.01.001

Genes

TRPV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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