An efficient method for high molecular weight bacterial DNA extraction suitable for shotgun metagenomics from skin swabs

Abstract excerpt

The human skin microbiome represents a variety of complex microbial ecosystems that play a key role in host health. Molecular methods to study these communities have been developed but have been largely limited to low-throughput quantification and short amplicon sequencing, providing limited functional information about the communities present. Shotgun metagenomic sequencing has emerged as a preferred method for m...

Topics

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• Bacteria
• Bacterial Identification and Susceptibility Testing
• Bacterial Typing Techniques
• Clostridium difficile and Clostridium perfringens research
• Dermatology and Skin Diseases
• Gut microbiota and health
• Infective Endocarditis Diagnosis and Management
• Orthopedic Infections and Treatments

Identifiers and source

Literature Corpus work

33a8b7c8-2588-5018-8bba-6ebc905076c0

DOI

10.1101/2023.02.23.529690